STIs may affect the whole penis and area around it or just one area. Some reasons for irritation include the following: Sexually transmitted infectionsĪ sexually transmitted infection (STI) may cause the penis to become irritated. Irritation may occur in one, multiple, or all areas of the penis. Foreskin: A penis may or may not have a foreskin, a piece of skin covering the tip.The pubis area: This is where the base of the penis connects between a person’s legs.The shaft: This is the main part of the penis and connects the tip to the pubis area.Doctors may also refer to this as the glans penis. The tip: The penis tip is the head of the penis.
